\documentclass{article}
\usepackage[utf8]{inputenc}
\usepackage[ngerman]{babel}
\usepackage{colortbl}
\begin{document}
\setlength\arrayrulewidth{2pt}
\begin{tabular}
{c!{\color[gray]{0.9}\vline}|c!{\color{cyan}\vline}c!{\color{red}\vline}}
eins&zwei\\
\arrayrulecolor{red}\hline
drei&vier \\
\arrayrulecolor{green}\cline{1-1}
fünf&sechs\\
\end{tabular}
\end{document}